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Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development | Nature Genetics
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Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease | Nature Genetics
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FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling | British Journal of Cancer
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Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development - ScienceDirect
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Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth | Nature Communications
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Down-regulated long non-coding RNA RNAZFHX4-AS1 suppresses invasion and migration of breast cancer cells via FAT4-dependent Hippo signaling pathway | Cancer Gene Therapy
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FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer | Journal of Experimental & Clinical Cancer Research | Full Text
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FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer | BMC Cancer | Full Text
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